Fresofol 1% MCT/LCT Caution For Usage

Pharmaceutical precautions: After first opening, the product must be used immediately.
Administration systems with undiluted Fresofol 1% MCT/LCT should be replaced after 12 hours.
Fresofol 1% MCT/LCT should not be mixed prior to administration with injection or infusion solutions other than glucose 50 mg/ml (5%) solution for injection or sodium chloride 9 mg/ml (0.9%) solution for injection or preservative-free lidocaine 10 mg/ml (1%) solution for injection. The maximum dilution must not exceed 1 part of Fresofol 1% MCT/LCT with 4 parts of glucose 50 mg/ml (5%) solution for injection or sodium chloride 9 mg/ml (0.9%) solution for injection (minimum concentration 2 g propofol/ml). The mixture should be prepared aseptically (controlled and validated conditions preserved) immediately prior to administration and must be administered within 6 hours after preparation (see also Dosage & Administration).
Final propofol concentration must not be below 2 mg/ml.
Co-administration of a glucose 50 mg/ml (5%) solution for injection or sodium chloride 9 mg/ml solution for injection or sodium chloride 1.8 mg/ml (0.18%) solution for injection and glucose 40 mg/ml (4%) solution for injection with Fresofol 1% MCT/LCT is permitted via a Y-piece connector close to the injection site.
Containers should be shaken before use. If two layers can be seen after shaking, the emulsion should not be used. Use only homogeneous preparations and undamaged containers.
Prior to use, the ampoule neck or rubber membrane should be cleaned using an alcohol spray or a swab dipped in alcohol. After use, tapped containers must be discarded.
For single use. Any unused emulsion must be discarded.
Do not throw away any medicines via wastewater or household waste. Ask the pharmacist how to throw away medicines no longer used. These measures will help protect the environment.
Incompatibilities: Fresofol 1% MCT/LCT should not be mixed prior to administration with injection or infusion solutions other than 5% w/v glucose solution or 0.9% w/v sodium chloride solution or 1% lidocaine injection solution (see Dosage & Administration). Final propofol concentration must not be below 2 mg/ml.